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readily be admitted, that the daily use of any article, which causes an exhaustion of the nervous power, beyond what is necessarily occasioned by unstimulating food and drink, and the ordinary physical agents, as heat, cold, light, together with mental and corporeal exertion, &c., is not only useless but hurtful, tending directly to produce disease and premature decay. Such is tobacco. Ample evidence of this is furnished by a departure, more or less obvious, from healthy action, in the organic, vital movements of a large majority of tobacco consumers.

From the habitual use of tobacco, in either of its forms of snuff, cud, or cigar, the following symptoms may arise; a sense of weakness, sinking, or pain at the pit of the stomach; dizziness or pain in the head; occasional dimness or temporary loss of sight; paleness and sallowness of the countenance, and sometimes swelling of the feet; an enfeebled state of the voluntary muscles, manifesting itself sometimes by tremors of the hands, sometimes by weakness, tremulousness, squeaking or hoarseness of the voice, rarely a loss of the voice; disturbed sleep, starting from the early slumbers with a sense of suffocation or the feeling of alarm; incubus, or nightmare; epileptic or convulsion fits; confusion or weakness of the mental faculties; peevishness and irritability of temper; instability of purpose; seasons of great depression of the spirits; long fits of unbroken melancholy and despondency, and, in some cases, entire and permanent mental derangement.2

The animal machine, by regular and persevering reiteration or habit, is capable of accommodating itself to impressions made by poisonous substances, so far as not to show signs of injury under a superficial observation, provided they are slight at first, and gradually increased, but it does not hence follow that such impressions are not hurtful. It is a great mistake, into which thousands are led, to suppose that every unfavorable effect or influence of an article of food, or drink, or luxury, must be felt immediately after it is taken. Physicians often have the opportunity of witnessing this among their patients.

The confirmed dyspeptic consults his physician for pain or wind in the stomach, accompanied with headache or dizziness, occasional pains of the limbs, or numbness or tremors in the hands and feet, and sometimes with difficult breathing, disturbed sleep, and a dry cough, and huskiness of the voice in the morning. The physician suggests the propriety of his laying aside animal food for a time; but the patient objects, alleging that he never feels so well as when he has swallowed a good dinner. He is then advised to avoid spirit, wine, cider, beer, &c.; the reply is, "it is impossible, that the little I take can do me hurt; so far from that, it always does me good; I always feel the better for it. I do not need any one to tell me about that." He is asked if he uses tobacco. "Yes, I smoke a little, chew a little, and snuff a little." You had better leave it off altogether, Sir. "Leave it off? I assure you, Doctor, you know but little about it. If I were to leave off smoking, I should throw up half my dinner." That might do you no harm, Sir. "I see you do not understand my case, Doctor; I have taken all these good things, for many years, and have enjoyed good health. They never injured me. How could they have done so without my perceiving it? Do you suppose I have lived so long in the world without knowing what does me good, and what does not?" It would appear so, Sir, and you are in a fair way to die, without acquiring this important knowledge.

The poor man goes away, in a struggle between the convictions of truth and the overwhelming force of confirmed habit. Under the sustaining power of a good constitution, and in the activity of business, he never dreamed of injury from the moderate indulgence, as he regarded it, in the use of stimulants, as spirit, wine, tobacco, &c., till the work was done. His is the case of hundreds of thousands.

The vital principle, in the human body, can so far resist the influences of a variety of poisons, slowly introduced into it, that their effects shall be unobserved, till, under the operation of an exciting or disturbing cause, their accumulated force breaks out, in the form of some fearful or incurable disease. The poison, which comes from vegetable decompositions, on extensive marshes and the borders of lakes, after being received into the body, remains apparently harmless, in some instances, a whole year, before it kindles up a wasting intermittent, or a destructive bilious remittent fever.

Facts of this nature show, that pernicious influences may be exerted upon the secret springs of life, while we are wholly unconscious of their operation. Such is the effect of the habitual use of tobacco and other narcotics, and of all stimulants which, like them, make an impression upon the whole nervous system, without affording the materials of supply or nutrition.

It is an alleged fact, that, previously to the age of forty years, a larger mortality exists in Spanish America than in Europe. The very general habit of smoking tobacco, existing among children and youth as well as adults, it has been supposed, and not without reason, might explain this great mortality. Like ardent spirits, tobacco must be peculiarly pernicious in childhood, when all the nervous energy is required to aid in accomplishing the full and perfect developement of the different organs of the body, and in ushering in the period of manhood. I once knew a boy, eight years of age, whose father had taught him the free use of the tobacco cud, four years before. He was a pale, thin, sickly child, and often vomited up his dinner.

To individuals of sedentary habits and literary pursuits, tobacco is peculiarly injurious, inasmuch as these classes of persons are, in a measure, deprived of the partially counteracting influence of air and exercise. I have prescribed for scores of young men, pursuing either college or professional studies, who had been more or less injured by the habitual use of this plant.

In the practice of smoking there is no small danger. It tends to produce a huskiness of the mouth, which calls for some liquid. Water is too insipid, as the nerves of taste are in a half-palsied state, from the influence of the tobacco smoke; hence, in order to be tasted, an article of a pungent or stimulating character is resorted to, and hence the kindred habits of smoking and drinking. A writer in one of the American periodicals, speaking of the effect of tobacco, in his own case, says, that smoking and chewing "produced a continual thirst for stimulating drinks; and this tormenting thirst led me into the habit of drinking ale, porter, brandy, and other kinds of spirit, even to the extent, at times, of partial intoxication." The same writer adds, that "after he had subdued his appetite for tobacco, he lost all desire for stimulating drinks." The snufftaker necessarily swallows a part of it, especially when asleep, by which means its enfeebling effects must be increased.

The opinion that tobacco is necessary to promote digestion is altogether erroneous. If it be capable of soothing the uneasiness of the nerves of the stomach, occurring after a meal, that very uneasiness has been caused by some error of diet or regimen, and may be removed by other means. If tobacco facilitate digestion, how comes it, that, after laying aside the habitual use of it, most individuals experience an increase of appetite and of digestive energy, and an accumulation of flesh?

It is sometimes urged, that men occasionally live to an advanced age, who are habitual consumers of this article; true, and so do some men who habitually drink rum, and who occasionally get drunk; and does it thence follow that rum is harmless or promotes long life? All, that either fact proves, is, that the poisonous influence is longer or more effectually resisted, by some constitutions than by others. The man, who can live long under the use of tobacco and rum, can live longer without them.

An opinion has prevailed in some communities, that the use of tobacco operates, as a preservative against infectious and epidemic diseases. This must be a mistake. Whatever tends to weaken or depress the powers of the nervous system predisposes it to be operated upon, by the causes of these diseases. If tobacco afford protection, in such cases, why does it not secure those who use it, against cholera? In no communities, perhaps, has that disease committed more frightful ravages, than where all classes of persons are addicted to the free use of this article. In Havana, in 1833, containing a stationary population of about one hundred and twenty thousand, cholera carried off, in a few weeks, if we may credit the public journals, sixteen thousand; and, in Matanzas, containing a population of about twelve thousand, it was announced that fifteen hundred perished. This makes one-eighth of the population in both places; and if, as in most other cities, the number of deaths, as published in the journals, falls short of the truth, and a considerable deduction be made from the whole population on account of the great numbers who fled on the appearance of the disease, the mortality will be still greater. In Havana, after the announcement of the foregoing mortality, and after a subsidence of the epidemic, for some weeks, it returned, and destroyed such numbers as to bring back the public alarm. The degree, in which the practice of smoking prevails, may be judged of by a fact, stated by Dr. Abbot in his Letters from Cuba, namely, that, in 1828, it was then the common estimate, that, in Havana, there was an average consumption of ten thousand dollars' worth of cigars in a day.

Dr. Moore, who resides in the province of Yucatan, in Mexico, assures me that the city of Campeachy, containing a population of twenty thousand, lost, by cholera, in about thirty days, commencing early in July, four thousand three hundred and a fraction, of its inhabitants. This is a little short of one-fourth of the population; although Dr. Moore says that the people of Campeachy make it as a common remark, "we have lost one in four of our number." With reference to the habits of the people in that part of Mexico, Dr. Moore says, "every body smokes cigars. I never saw an exception among the natives. It is a common thing to see a child of two years old learning to smoke."

The opinion, that the use of tobacco preserves the teeth, is supported neither by physiology nor observation. Constantly applied to the interior of the mouth, whether in the form of cud or of smoke, this narcotic must tend to enfeeble the gums, and the membrane covering the necks and roots of the teeth, and, in this way, must rather accelerate than retard their decay. We accordingly find, that tobacco consumers are not favored with better teeth than others; and, on the average, they exhibit these organs in a less perfect state of preservation. Sailors make a free use of tobacco and they have bad teeth.

The grinding surfaces of the teeth are, on the average, more rapidly worn down or absorbed, from the chewing or smoking of tobacco for a series of years; being observed in some instances to project but a little way beyond the gums. This fact I have observed, in the mouths of some scores of individuals in our own communities, and I have also observed the same thing in the teeth of several men, belonging to the Seneca and St. Francois tribes of Indians, who, like most of the other North American tribes, are

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