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flatulent colic.

Star anise has an aromatic taste, slightly bitter and acrid, and a very marked perfume of anise which with its star-like form gives the plant one of its names. It is a very useful stimulant, tonic, stomachic and carminative.

It is official in all Pharmacopœias and the pericarp is the part employed.

The dose is from 1 to 2 grams to 100 of water in infusion, to be taken in one draught.

According to Schlegel it contains the following substances: An essential oil 4.675; a green waxy material which melts at 51°, a resin, a gum and saponin. The essential oil is (almost) identical with that of anise from which it is impossible to distinguish it chemically. The only difference is that the former has a blander odor and solidifies at 1°.25 instead of 10°, as does the oil of anise.

Botanical Description.—The plant grows in the mountains of Yunnan, China, and in Tonquin. The part used in the Philippines is the fruit, being indeed the only part known here. This is composed of 8 woody follicles arranged about a central column in the form of a star. These follicles open at maturity and reveal the seeds, which are shining, smooth, ovoid, hard, of a pretty chestnut-red color. In the Philippines they are sold even in the smallest food-vending shops.

Michelia Champaca, L.

Nom. Vulg.—Tsampaka, Sampaka, Tag.; Champaca, Fil.-Span.

Uses.—The bark of the trunk is well known as a febrifuge and emmenagogue in India. It is slightly bitter and aromatic. Dr. H. Folliat has used it with success in the Island of Mauritius in the treatment of the common intermittent fevers; he administered the infusion (bark 30 grams, water 600 cc.)—or the decoction (bark 30 grams, water 1,200 cc.); boil till reduced to 600 cc.—giving a wine-glassful every hour just before and after the paroxysm.

An astringent decoction made from the leaves is used as a gargle in sore throat. The root is emmenagogue and the seeds are used in the treatment of anal fissure.

Dr. Hooper has found the following substances in the bark of the Champana: a volatile oil with a pine-like odor; a fixed oil, insoluble in alcohol, melting at 15° and forming soap with soda; a resin extremely bitter, acrid, brown in color; tannin; sugar; a bitter principle, albuminoids, coloring matters, mucilage and starch.

Botanical Description.—A tree 15–18° high; leaves alternate, 6 × 2′, stipulate, simple. Flowers fragrant, saffron-colored, hermaphrodite, solitary and axillary. The receptacle, conical at its base, becomes narrow, lengthens and then enlarges, forming a column which is bare at its narrow part. At its base is inserted the perianth composed of 6 overlapping leaflets arranged in two series. Stamens indefinite, fixed in the base of the column of the receptacle on the superior portion of which are inserted the ovaries which contain many ovules arranged in two vertical series.

Habitat.—Common in all parts (of the islands).

Anonaceæ.

Custard-Apple Family.

Artabotrys odoratissimus, R. Br. (A. hamatus, Bl.; Uvaria Sinensis and Unona uncinata, Blanco.)

Nom. Vulg.—Ilag̃-ilag̃ de China, Sp.-Fil.; Alag̃-ilag̃ Son-son, Tag.

Uses.—A decoction of the leaves of this species is used to treat cholera in some of the islands of the Malay group; in the island of Java they use for the same purpose a decoction of the leaves of the species A. suaveolens, Bl., which is commonly called Susog̃ Damulog in the Pampanga dialect. The active principles of these plants are so powerful that one must beware of giving a large dose, as hemorrhages, nervous phenomena and abortion may follow.

Botanical Description.—A tree 15–18° high with leaves alternate, lanceolate, glabrous, and petioles very short. Flowers very sweet, axillary, solitary. Petals 6, fleshy, concave at the base. Stamens indefinite, closely packed, overlapping. Peduncle curved like a crook.

Habitat.—Cultivated in gardens.

Anona squamosa, L. (A. tuberosa, Rumph.)

Nom. Vulg.—Ates, Tag.; Custard Apple, Eng.

Uses.—The fruit of the mature ates is edible and is one of the most delicious that grows in the Philippines; its white and delicately perfumed pulp has a delicious flavor. The unripe fruit is exceedingly astringent. The fermented juice of the ripe pulp is used in certain parts of America to prepare a popular drink. The powdered seeds make a useful parasiticide especially when used on the scalp, but it is necessary to avoid getting any of the drug in the eyes on account of its irritant effect.

Botanical Description.—Tree 8 or 9° high with leaves alternate, oblong, the edges pubescent. Flowers greenish-yellow, axillary, solitary; peduncle not curved. Petals 6, convergent. Stamens crowded, indefinite. Fruit fleshy, covered with scales or rather rounded tubercles; beneath is the white and fragment pulp, covering the long-oval seeds.

A. reticulate, L.

Nom. Vulg.—Anonas, Sp.-Fil.

Uses.—The fruit of this species is neither as much prized nor as abundant in the Philippines as that of the ates. When unripe it possesses the same properties as the latter. The large proportion of tannin which both species contain in their unripe state, makes them very useful in treating diarrhœa and dysentery. They are administered in the form of a decoction, by enema. The sap of the trunk is very irritating. The roots are used by the American Indians to treat epilepsy. Lemon juice is the antidote for the sap of this species.

I wish to call attention to the similarity of the common name of this plant to another entirely distinct species commonly used in the Tagalo therapeutics; namely, the anonag̃ (Cordia), with which it must not be confused.

Botanical Description.—Tree 10° high with leaves lanceolate, pubescent. Flowers in a sort of umbel. Corolla like that of A. squamosa. Fruit without the plainly visible tubercles of the foregoing species, their presence being merely suggested by a sort of net traced on the surface.

A. muricata, L.

Nom. Vulg.—Guanábano, Goyabano, Sp.-Fil.

Uses.—The ripe fruit possesses antiscorbutic properties; the unripe fruit is used in treating dysentery. It is said that the ripe fruit is used in diseases of the liver.

Botanical Description.—Tree with leaves oval, alternate and glabrous. Flower solitary, terminal, whitish. The fruit is much larger than that of the other species, is covered with scales that end in a soft point or thorn and has a very pronounced acid taste.

Habitat.—All three species are common in all parts of the Archipelago.

Menispermaceæ.

Moonseed Family.

Tinospora crispa, Miers. (Menispermum crispum, L.; M. rimosum, Blanco; Cocculus crispus, DC.)

Nom. Vulg.—Makabuhay, Tag.

Uses.—Makabuhay is one of the most widely known and used plants in the Philippines; a sort of panacea applied to all bodily afflictions. Its Tagalo name means literally “you may live.” A shoot deprived of roots and dropped in some moist place is soon covered with bright green leaves and adventitious roots. This peculiarity of the plant made it possible for me to take a large number of sprouts from Manila to Paris where they arrived perfectly fresh after a voyage of forty days, during which they lay almost forgotten in the ship and the cars.

The stem is the part employed in medicine. A decoction is given internally in the various forms of malarial fever and of dyspepsia. Externally it is most useful as a wash for ulcers of all kinds, rapidly improving their appearance.

In India the species T. cordifolia is used; it differs but little from T. crispa. It is official in the Pharmacopœia and has been introduced into Europe. T. cordifolia has given excellent results in the mild forms of intermittent fever; in general debility following long and severe cases of illness; in chronic rheumatism, and in the second stage of syphilis. As the two species are so much alike we shall add the preparations and dose of T. cordifolia which we have used on several occasions with good results.

Tincture of T. cordifolia.—Stems of the dried plant, 100 grams. Alcohol 21° (Cartier), 500 cc. Macerate seven days in a closed vessel stirring from time to time. After decanting add enough alcohol (21°) to bring the quantity up to 500 cc., and filter.

Dose.—4–8 grams.

Maceration.—Fresh stems cut in small pieces, 30 grams, water 300 grams. Macerate for two hours and filter.

Dose.—30–90 cc. a day.

Extract.—Dry makabuhay in small pieces 500 grams. Water 2½ liters. Macerate for twelve hours, filter the liquid and express the macerated drug which is then macerated a second time in 2½ liters of water. Express again, unite the two liquids and filter. Evaporate in a water-bath to the consistency of a pill mass.

Dose.—½–1½ grams a day in fractional doses.

Botanical Description.—A vine whose runners entwine themselves among the tops of the highest trees, giving off many adventitious roots which seek the earth. The stem is covered with projecting tubercles. Leaves heart-shaped, pointed, entire with five well-marked nerves. Flowers yellowish-green, diœcious, growing in axillary racemes. The male flowers have a corolla of six petals, the three smaller ones arranged alternately. In the female flower the stamens are represented by three glands situated at the base of the petals. Fruit, an elliptical drupe.

Anamirta Cocculus, Wight & Arn. (Menispermum Cocculus, (L.) Blanco; M. lacunosum, Famk; Cocculus lacunosus, C. suberosus, DC.)

Nom. Vulg.—Laktag̃, Liktag̃, Suma, Lanta, Lintag̃ bagin, Tuba, Balasin, Bayati, Tag., Vis., Pam.

Uses.—One of the uses to which the India berries (Cocas de Levante) are put in the Philippines, is to throw them into small sluggish streams or into lakes with the object of intoxicating the fish which soon come to the surface and float there as if dead. This custom is very extensive in Malaysia, in India and even in Europe, where, in order to avoid the cases of poisoning which this practice has occasioned in the consumers of fish taken in this way, it has been found necessary to forbid the sale of the berries except in the pharmacies. These restrictions are practiced in France.

In the Binondo market in Manila the root of this plant may be found in abundance; it is yellow and very bitter. The natives use the infusion (5–10 grams to 300 cc. of water) in fevers, dyspepsia and menstrual derangements. In India also the root is used in the same complaints.

The fruit contains the highly toxic principle picrotoxin, and others as follows:

Menispermin (C18H24N2O2) is an alkaloid which crystallizes in pyramidal prisms, is soluble in alcohol and ether and insoluble in water. Hot nitric acid converts it into oxalic acid and a yellow substance of a resinous appearance.

Picrotoxin (C30H24O13) is not an alkaloid as may be seen from its formula. Its properties are not well known at the present time. It crystallizes in small quadrilateral prisms, white and transparent, or in needles grouped in stars. No odor, taste bitter, insoluble in water, partly soluble in alcohol and in ether, freely soluble in acids and alkalies. A solution in concentrated sulphuric acid has a saffron-yellow color. Nitric acid transforms it into oxalic acid.

Picrotoxinin exists in picrotoxin in the proportion of 32 to 100, and may be separated by boiling in benzine. It is bitter, poisonous, reduced by Fehling’s solution and nitrate of silver. Sixty-six per cent. of picrotoxin consists of another bitter substance, non-poisonous—picrotin, which is insoluble in benzine and is reduced by Fehling’s solution and nitrate of silver. Lastly, anamirtin is found in the mother water of picrotoxin; it is not bitter, not poisonous, and not reducible by the aforementioned reagents.

The fruit of the anamirta, the “coca de Levante” is an acrid, narcotic poison, which may not be employed internally; its uses are limited to external medication. In the Pharmacopœia of India is given the formula for a parasiticide ointment, highly recommended in the treatment of pediculi:

Unguentum anamirtæ:

4 grams Cocculus berries, powdered, 30 grams Vaseline. M. Fiat unguentum.

In applying this ointment it is necessary to make sure that there is no wound or abrasion of the skin through which absorption might take place.

Botanical Description.—A vine with

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