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of a fine wide August morning, and as he ceased his swift work, as taut nerves slackened, he looked out of his lofty window and was conscious of the world below: bright roofs, jubilant towers, and a high-decked Sound steamer swaggering up the glossy river.

He was completely fagged; he was, like a surgeon after a battle, like a reporter during an earthquake, perhaps a little insane; but sleepy he was not. He cursed the delay involved in the growth of the bacteria, without which he could not discover the effect of the various sorts of broths and bacterial strains, but choked his impatience.

He mounted the noisy slate stairway to the lofty world of the roof. He listened at the door of the Institute’s animal house. The guinea pigs, awake and nibbling, were making a sound like that of a wet cloth rubbed on glass in window-cleaning. He stamped his foot, and in fright they broke out in their strange sound of fear, like the cooing of doves.

He marched violently up and down, refreshed by the soaring sky, till he was calmed to hunger. Again he went pillaging. He found chocolate belonging to an innocent technician; he even invaded the office of the Director and in the desk of the Diana-like Pearl Robbins unearthed tea and a kettle (as well as a lipstick, and a love-letter beginning “My Little Ickles”). He made himself a profoundly bad cup of tea, then, his whole body dragging, returned to his table to set down elaborately, in a shabby, nearly-filled notebook, every step of his experiment.

After seven he worked out the operation of the telephone switchboard and called Lower Manhattan Hospital. Could Dr. Arrowsmith have some more pus from the same carbuncle? What? It’d healed? Curse it! No more of that material.

He hesitated over waiting for Gottlieb’s arrival, to tell him of the discovery, but determined to keep silence till he should have determined whether it was an accident. Eyes wide, too wrought up to sleep in the subway, he fled uptown to tell Leora. He had to tell someone! Waves of fear, doubt, certainty, and fear again swept over him; his ears rang and his hands trembled.

He rushed up to the flat; he bawled “Lee! Lee!” Before he had unlocked the door. And she was gone.

He gaped. The flat breathed emptiness. He searched it again. She had slept there, she had had a cup of coffee, but she had vanished.

He was at once worried lest there had been an accident, and furious that she should not have been here at the great hour. Sullenly he made breakfast for himself⁠ ⁠… It is strange that excellent bacteriologists and chemists should scramble eggs so waterily, should make such bitter coffee and be so casual about dirty spoons⁠ ⁠… By the time he had finished the mess he was ready to believe that Leora had left him forever. He quavered, “I’ve neglected her a lot.” Sluggishly, an old man now, he started for the Institute, and at the entrance to the subway he met her.

She wailed, “I was so worried! I couldn’t get you on the phone. I went clear down to the Institute to see what’d happened to you.”

He kissed her, very competently, and raved, “God, woman, I’ve got it! The real big stuff! I’ve found something, not a chemical you put in I mean, that eats bugs⁠—dissolves ’em⁠—kills ’em. May be a big new step in therapeutics. Oh, no, rats, I don’t suppose it really is. Prob’ly just another of my bulls.”

She sought to reassure him but he did not wait. He dashed down to the subway, promising to telephone to her. By ten, he was peering into his incubator.

There was a cloudy appearance of bacteria in all the flasks except those in which he had used broth from the original alarming flask. In these, the mysterious murderer of germs had prevented the growth of the new bacteria which he had introduced.

“Great stuff,” he said.

He returned the flasks to the incubator, recorded his observations, went again to the library, and searched handbooks, bound proceedings of societies, periodicals in three languages. He had acquired a reasonable scientific French and German. It is doubtful whether he could have bought a drink or asked the way to the Kursaal in either language, but he understood the universal Hellenistic scientific jargon, and he pawed through the heavy books, rubbing his eyes, which were filled with salty fire.

He remembered that he was an army officer and had lipovaccine to make this morning. He went to work, but he was so twitchy that he ruined the batch, called his patient garçon a fool, and after this injustice sent him out for a pint of whisky.

He had to have a confidant. He telephoned to Leora, lunched with her expensively, and asserted, “It still looks as if there were something to it.” He was back in the Institute every hour that afternoon, glancing at his flasks, but between he tramped the streets, creaking with weariness, drinking too much coffee.

Every five minutes it came to him, as a quite new and ecstatic idea, “Why don’t I go to sleep?” then he remembered, and groaned, “No, I’ve got to keep going and watch every step. Can’t leave it, or I’ll have to begin all over again. But I’m so sleepy! Why don’t I go to sleep?”

He dug down, before six, into a new layer of strength, and at six his examination showed that the flasks containing the original broth still had no growth of bacteria, and the flasks which he had seeded with the original pus had, like the first eccentric flask, after beginning to display a good growth of bacteria cleared up again under the slowly developing attack of the unknown assassin.

He sat down, drooping with relief. He had it! He stated in the conclusions of his first notes:

“I have observed a principle, which I shall temporarily call the X Principle, in pus from a staphylococcus infection, which checks the growth of several strains of staphylococcus, and

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