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on inmates of the Texas penal system; a recording of that talk, complete with visual aids, is available online1; curious readers with half an hour to kill are refered there for details not only on vampire biology, but on the research, funding, and “ethical and political concerns” regarding vampire domestication (not to mention the ill-fated “Taming Yesterday’s Nightmares For A Brighter Tomorrow” campaign). The following (much briefer) synopsis restricts itself to a few biological characteristics of the ancestral organism:

Homo sapiens vampiris was a short-lived Human subspecies which diverged from the ancestral line between 800,000 and 500,000 year BP. More gracile than either neandertal or sapiens, gross physical divergence from sapiens included slight elongation of canines, mandibles, and long bones in service of an increasingly predatory lifestyle. Due to the relatively brief lifespan of this lineage, these changes were not extensive and overlapped considerably with conspecific allometries; differences become diagnostically significant only at large sample sizes (N>130).

However, while virtually identical to modern humans in terms of gross physical morphology, vampiris was radically divergent from sapiens on the biochemical, neurological, and soft-tissue levels. The GI tract was foreshortened and secreted a distinct range of enzymes more suited to a carnivorous diet. Since cannibalism carries with it a high risk of prionic infection2, the vampire immune system displayed great resistance to prion diseases3, as well as to a variety of helminth and anasakid parasites. Vampiris hearing and vision were superior to that of sapiens; vampire retinas were quadrochromatic (containing four types of cones, compared to only three among baseline humans); the fourth cone type, common to nocturnal predators ranging from cats to snakes, was tuned to near-infrared. Vampire grey matter was “underconnected” compared to Human norms due to a relative lack of interstitial white matter; this forced isolated cortical modules to become self-contained and hypereffective, leading to omnisavantic pattern-matching and analytical skills4.

Virtually all of these adaptations are cascade effects that— while resulting from a variety of proximate causes— can ultimately be traced back to a paracentric inversion mutation on the Xq21.3 block of the X-chromosome5. This resulted in functional changes to genes coding for protocadherins (proteins that play a critical role in brain and central nervous system development). While this provoked radical neurological and behavioral changes, significant physical changes were limited to soft tissue and microstructures that do not fossilise. This, coupled with extremely low numbers of vampire even at peak population levels (existing as they did at the tip of the trophic pyramid) explains their virtual absence from the fossil record.

Significant deleterious effects also resulted from this cascade. For example, vampires lost the ability to code for -Protocadherin Y, whose genes are found exclusively on the hominid Y chromosome6. Unable to synthesise this vital protein themselves, vampires had to obtain it from their food. Human prey thus comprised an essential component of their diet, but a relatively slow-breeding one (a unique situation, since prey usually outproduce their predators by at least an order of magnitude). Normally this dynamic would be utterly unsustainable: vampires would predate humans to extinction, and then die off themselves for lack of essential nutrients.

Extended periods of lungfish-like dormancy7 (the so-called “undead” state)—and the consequent drastic reduction in vampire energetic needs— developed as a means of redressing this imbalance. To this end vampires produced elevated levels of endogenous Ala-(D) Leuenkephalin (a mammalian hibernation-inducing peptide8) and dobutamine, which strengthens the heart muscle during periods on inactivity9.

Another deleterious cascade effect was the so-called “Crucifix Glitch”— a cross-wiring of normally-distinct receptor arrays in the visual cortex10, resulting in grand mal-like feedback siezures whenever the arrays processing vertical and horizontal stimuli fired simultaneously across a sufficiently large arc of the visual field. Since intersecting right angles are virtually nonexistent in nature, natural selection did not weed out the Glitch until H. sapiens sapiens developed Euclidean architecture; by then, the trait had become fixed across H. sapiens vampiris via genetic drift, and—suddenly denied access to its prey—the entire subspecies went extinct shortly after the dawn of recorded history.

You’ll have noticed that Jukka Sarasti, like all reconstructed vampires, sometimes clicked to himself when thinking. This is thought to hail from an ancestral language, which was hardwired into a click-speech mode more than 50,000 years BP. Click-based speech is especially suited to predators stalking prey on savannah grasslands (the clicks mimic the rustling of grasses, allowing communication without spooking quarry)11. The Human language most closely akin to Old Vampire is Hadzane12.

Sleight of Mind

The Human sensorium is remarkably easy to hack; our visual system has been described as an improvised “bag of tricks”13 at best. Our sense organs acquire such fragmentary, imperfect input that the brain has to interpret their data using rules of probability rather than direct perception14. It doesn’t so much see the world as make an educated guess about it. As a result, “improbable” stimuli tends to go unprocessed at the conscious level, no matter how strong the input. We tend to simply ignore sights and sound that don’t fit with our worldview.

Sarasti was right: Rorschach wouldn’t do anything to you that you don’t already do to yourself.

For example, the invisibility trick of that young, dumb scrambler— the one who restricted its movement to the gaps in Human vision— occured to me while reading about something called inattentional blindness. A Russian guy called Yarbus was the first to figure out the whole saccadal glitch in Human vision, back in the nineteen sixties15. Since then, a variety of researchers have made objects pop in and out of the visual field unnoticed, conducted conversations with hapless subjects who never realised that their conversational partner had changed halfway through the interview, and generally proven that the Human brain just fails to notice an awful lot of what’s going on around it16, 17, 18. Check out the demos at the website of the Visual Cognition Lab at the University of Illinois19 and you’ll see what I mean. This really is rather mindblowing, people. There could be Scientologists walking among us right now and if they moved just right, we’d never even see them.

Most of the psychoses, syndromes, and hallucinations described herein are real, and are described in detail by Metzinger20, Wegner21, and/or Saks22 (see also Sentience/Intelligence, below_)_. Others (_e.g._ Grey Syndrome) have not yet made their way into the DSM23—truth be told, I invented a couple— but are nonetheless based on actual experimental evidence. Depending upon whom you believe, the judicious application of magnetic fields to the brain can provoke everything from religious rapture24 to a sense of being abducted by aliens25. Transcranial magnetic stimulation can change mood, induce blindness26, or target the speech centers (making one unable to pronounce verbs, for example, while leaving the nouns unimpaired)27. Memory and learning can be enhanced (or impaired), and the US Government is presently funding research into wearable TMS gear for—you guessed it— military purposes28.

Sometimes electrical stimulation of the brain induces “alien hand syndrome”— the involuntary movement of the body against the will of the “person” allegedly in control29. Other times it provokes equally involuntary movements, which subjects nonetheless insist they “chose” to perform despite overwhelming empirical evidence to the contrary30_. Put all this together with the fact that the body begins to act before the brain even “decides” to move31 (but see32, 33), and the whole concept of free will_—despite the undeniable subjective feeling that it’s real—begins to look a teeny bit silly, even outside the influence of alien artefacts.

While electromagnetic stimulation is currently the most trendy approach to hacking the brain, it’s hardly the only one. Gross physical disturbances ranging from tumors34 to tamping irons35 can turn normal people into psychopaths and pedophiles (hence that new persona sprouting in Susan James’s head). Spirit possession and rapture can be induced through the sheer emotional bump-and-grind of religious rituals, using no invasive neurological tools at all (and not even necessarily any pharmacological ones)21. People can even develop a sense of ownership of body parts that aren’t theirs, can be convinced that a rubber hand is their real one36. Vision trumps propioreception: a prop limb, subtly manipulated, is enough to convince us that we’re doing one thing while in fact we’re doing something else entirely37, 38.

The latest tool in this arsenal is ultrasound: less invasive than electromagnetics, more precise than charismatic revival, it can be used to boot up brain activity39 without any of those pesky electrodes or magnetic hairnets. In Blindsight it serves as a convenient back door to explain why Rorschach‘s hallucinations persist even in the presence of Faraday shielding— but in the here and now, Sony has been renewing an annual patent for a machine which uses ultrasonics to implant “sensory experiences” directly into the brain40. They’re calling it an entertainment device with massive applications for online gaming. Uh huh. And if you can implant sights and sounds into someone’s head from a distance, why not implant political beliefs and the irresistable desire for a certain brand of beer while you’re at it?

Are We There Yet?

The “telematter” drive that gets our characters to the story is based on teleportation studies reported in Nature41, Science,42,43 Physical Review Letters44, and (more recently) everyone and their doge.g., 45. The idea of transmitting antimatter specs as a fuel template is, so far as I know, all mine. To derive plausible guesses for Theseus‘s fuel mass, accelleration, and travel time I resorted to The Relativistic Rocket46, maintained by the mathematical physicist John Baez at UC Riverside. Theseus‘ use of magnetic fields as radiation shielding is based on research out of MIT47. I parked the (solar powered) Icarus Array right next to the sun because the production of antimatter is likely to remain an extremely energy-expensive process for the near future48, 49.

The undead state in which Theseus carries her crew is, of course, another iteration of the venerable suspended animation riff (although I’d like to think I’ve broken new ground by invoking vampire physiology as the mechanism). Two recent studies have put the prospect of induced hibernation closer to realization. Blackstone et al. have induced hibernation in mice by the astonishingly-simple expedient of exposing them to hydrogen sulfide50; this gums up their cellular machinery enough to reduce metabolism by 90%. More dramatically (and invasively), researchers at Safar Center for Resuscitation Research in Pittsburgh claim51 to have resurrected a dog three hours after clinical death, via a technique in which the animal’s blood supply was replaced by an ice-sold saline solution52. Of these techniques, the first is probably closer to what I envisioned, although I’d finished the first draft before either headline broke. I considered rejigging my crypt scenes to include mention of hydrogen sulfide, but ultimately decided that fart jokes would have ruined the mood.

The Game Board

Blindsight describes Big Ben as an “Oasa Emitter”. Officially there’s no such label, but Yumiko Oasa has reported finding hitherto-undocumented infrared emitters53, 54 — dimmer than brown dwarves, but possibly more common55,56— ranging in mass from three to thirteen Jovian masses. My story needed something relatively local, large enough to sustain a superJovian magnetic field, but small and dim enough to plausibly avoid discovery for the next seventy or eighty years. Oasa’s emitters suit my needs reasonably well (notwithstanding some evident skepticism over whether they actually exist57).

Of course I had to extrapolate on the details, given how little is actually known about these beasts. To this end I pilfered data from a variety of sources on gas giants58, 59, 60, 61, 62, 63, 64 and/or brown dwarves65, 66, 67, 68, 69, 70, 71, 72, , 73, 74, 75, scaling up or down as appropriate. From a distance, the firing of Rorschach‘s ultimate weapon looks an awful lot like the supermassive x-ray and radio flare recently seen erupting from a brown dwarf that

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