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purified in the same way.

The iodine method of disinfecting the skin introduced by Grossich is simple, and equally efficient. The day before operation the skin, after being washed with soap and water, is shaved, dehydrated by means of methylated spirit, and then painted with a 5 per cent. solution of iodine in rectified spirit. The painting with iodine is repeated just before the operation commences, and again after it is completed. The final application is omitted in the case of children. In emergency operations the skin is shaved dry and dehydrated with spirit, after which the iodine is applied as described above. The staining of the skin is an advantage, as it enables the operator to recognise the area that has been prepared.

If any acne pustules or infected sinuses are present, they should be destroyed or purified by means of the thermo-cautery or pure carbolic acid, after the patient is anæsthetised.

Appliances used at Operation.—Instruments that are not damaged by heat must be boiled in a fish-kettle or other suitable steriliser for fifteen minutes in a 1 per cent. solution of cresol or washing soda. Just before the operation begins they are removed in the tray of the steriliser and placed on a sterilised towel within reach of the surgeon or his assistant. Knives and instruments that are liable to be damaged by heat should be purified by being soaked in pure cresol for a few minutes, or in 1 in 20 carbolic for at least an hour.

Pads of Gauze sterilised by compressed circulating steam have almost entirely superseded marine sponges for operative purposes. To avoid the risk of leaving swabs in the peritoneal cavity, large square pads of gauze, to one corner of which a piece of strong tape about a foot long is securely stitched, should be employed. They should be removed from the caskets in which they are sterilised by means of sterilised forceps, and handed direct to the surgeon. The assistant who attends to the swabs should wear sterilised gloves.

Ligatures and Sutures.—To avoid the risk of implanting infective matter in a wound by means of the materials used for ligatures and sutures, great care must be taken in their preparation.

Catgut.—The following methods of preparing catgut have proved satisfactory: (1) The gut is soaked in juniper oil for at least a month; the juniper oil is then removed by ether and alcohol, and the gut preserved in 1 in 1000 solution of corrosive sublimate in alcohol (Kocher). (2) The gut is placed in a brass receiver and boiled for three-quarters of an hour in a solution consisting of 85 per cent. absolute alcohol, 10 per cent. water, and 5 per cent. carbolic acid, and is then stored in 90 per cent. alcohol. (3) Cladius recommends that the catgut, just as it is bought from the dealers, be loosely rolled on a spool, and then immersed in a solution of—iodine, 1 part; iodide of potassium, 1 part; distilled water, 100 parts. At the end of eight days it is ready for use. Moschcowitz has found that the tensile strength of catgut so prepared is increased if it is kept dry in a sterile vessel, instead of being left indefinitely in the iodine solution. If Salkindsohn's formula is used—tincture of iodine, 1 part; proof spirit, 15 parts—the gut can be kept permanently in the solution without becoming brittle. To avoid contamination from the hands, catgut should be removed from the bottle with aseptic forceps and passed direct to the surgeon. Any portion unused should be thrown away.

Silk is prepared by being soaked for twelve hours in ether, for other twelve in alcohol, and then boiled for ten minutes in 1 in 1000 sublimate solution. It is then wound on spools with purified hands protected by sterilised gloves, and kept in absolute alcohol. Before an operation the silk is again boiled for ten minutes in the same solution, and is used directly from this (Kocher). Linen thread is sterilised in the same way as silk.

Fishing-gut and silver wire, as well as the needles, should be boiled along with the instruments. Horse-hair and fishing-gut may be sterilised by prolonged immersion in 1 in 20 carbolic, or in the iodine solutions employed to sterilise catgut.

The field of operation is surrounded by sterilised towels, clipped to the edges of the wound, and securely fixed in position so that no contamination may take place from the surroundings.

The surgeon and his assistants, including the anæsthetist, wear overalls sterilised by steam. To avoid the risk of infection from dust, scurf, or drops of perspiration falling from the head, the surgeon and his assistants may wear sterilised cotton caps. To obviate the risk of infection taking place by drops of saliva projected from the mouth in talking or coughing in the vicinity of a wound, a simple mask may be worn.

The risk of infection from the air is now known to be very small, so long as there is no excess of floating dust. All sweeping, dusting, and disturbing of curtains, blinds, or furniture must therefore be avoided before or during an operation.

It has been shown that the presence of spectators increases the number of organisms in the atmosphere. In teaching clinics, therefore, the risk from air infection is greater than in private practice.

To facilitate primary union, all hæmorrhage should be arrested, and the accumulation of fluid in the wound prevented. When much oozing is anticipated, a glass or rubber drainage-tube is inserted through a small opening specially made for the purpose. In aseptic wounds the tube may be removed in from twenty-four to forty-eight hours, and where it is important to avoid a scar, the opening should be closed with a Michel's clip; in infected wounds the tube must remain as long as the discharge continues.

The fascia and skin should be brought into accurate apposition by sutures. If any cavity exists in the deeper part of the wound it should be obliterated by buried sutures, or by so adjusting the dressing as to bring its walls into apposition.

If these precautions have been successful, the wound will heal under the original dressing, which need not be interfered with for from seven to ten days, according to the nature of the case.

Dressings.—Gauze, sterilised by heat, is almost universally employed for the dressing of wounds. Double cyanide gauze may be used in such regions as the neck, axilla, or groin, where complete sterilisation of the skin is difficult to attain, and where it is desirable to leave the dressing undisturbed for ten days or more. Iodoform or bismuth gauze is of special value for the packing of wounds treated by the open method.

One variety or another of wool, rendered absorbent by the extraction of its fat, and sterilised by heat, forms a part of almost every surgical dressing, and various antiseptic agents may be added to it. Of these, corrosive sublimate is the most generally used. Wood-wool dressings are more highly and more uniformly absorbent than cotton wools. As evaporation takes place through wool dressings, the discharge becomes dried, and so forms an unfavourable medium for bacterial growth.

Pads of sphagnum moss, sterilised by heat, are highly absorbent, and being economical are used when there is much discharge, and in cases where a leakage of urine has to be soaked up.

Means adopted to combat Infection.—As has already been indicated, the same antiseptic precautions are to be taken in dealing with infected as with aseptic wounds.

In recent injuries such as result from railway or machinery accidents, with bruising and crushing of the tissues and grinding of gross dirt into the wounds, the scissors must be freely used to remove the tissues that have been devitalised or impregnated with foreign material. Hair-covered parts should be shaved and the surrounding skin painted with iodine. Crushed and contaminated portions of bone should be chiselled away. Opinions differ as to the benefit derived from washing such wounds with chemical antiseptics, which are liable to devitalise the tissues with which they come in contact, and so render them less able to resist the action of any organisms that may remain in them. All are agreed, however, that free washing with normal salt solution is useful in mechanically cleansing the injured parts. Peroxide of hydrogen sprayed over such wounds is also beneficial in virtue of its oxidising properties. Efficient drainage must be provided, and stitches should be used sparingly, if at all.

The best way in which to treat such wounds is by the open method. This consists in packing the wound with iodoform or bismuth gauze, which is left in position as long as it adheres to the raw surface. The packing may be renewed at intervals until the wound is filled by granulations; or, in the course of a few days when it becomes evident that the infection has been overcome, secondary sutures may be introduced and the edges drawn together, provision being made at the ends for further packing or for drainage-tubes.

If earth or street dirt has entered the wound, the surface may with advantage be painted over with pure carbolic acid, as virulent organisms, such as those of tetanus or spreading gangrene, are liable to be present. Prophylactic injection of tetanus antitoxin may be indicated.

CHAPTER XIII
CONSTITUTIONAL EFFECTS OF INJURIES Syncope —Shock —Collapse —Fat Embolism —Traumatic Asphyxia —Delirium in Surgical Patients: Delirium in general; Delirium tremens; Traumatic delirium. Syncope, Shock, and Collapse

Syncope, shock, and collapse are clinical conditions which, although depending on different causes, bear a superficial resemblance to one another.

Syncope or Fainting.—Syncope is the result of a suddenly produced anæmia of the brain from temporary weakening or arrest of the heart's action. In surgical practice, this condition is usually observed in nervous persons who have been subjected to pain, as in the reduction of a dislocation or the incision of a whitlow; or in those who have rapidly lost a considerable quantity of blood. It may also follow the sudden withdrawal of fluid from a large cavity, as in tapping an abdomen for ascites, or withdrawing fluid from the pleural cavity. Syncope sometimes occurs also during the administration of a general anæsthetic, especially if there is a tendency to sickness and the patient is not completely under. During an operation the onset of syncope is often recognised by the cessation of oozing from the divided vessels before the general symptoms become manifest.

Clinical Features.—When a person is about to faint he feels giddy, has surging sounds in his ears, and haziness of vision; he yawns, becomes pale and sick, and a free flow of saliva takes place into the mouth. The pupils dilate; the pulse becomes small and almost imperceptible; the respirations shallow and hurried; consciousness gradually fades away, and he falls in a heap on the floor.

Sometimes vomiting ensues before the patient completely loses consciousness, and the muscular exertion entailed may ward off the actual faint. This is frequently seen in threatened syncopal attacks during chloroform administration.

Recovery begins in a few seconds, the patient sighing or gasping, or, it may be, vomiting; the strength of the pulse gradually increases, and consciousness slowly returns. In some cases, however, syncope is fatal.

Treatment.—The head should at once be lowered—in imitation of nature's method—to encourage the flow of blood to the brain, the patient, if necessary, being held up by the heels. All tight clothing, especially round the neck or chest, must be loosened. The heart may be stimulated reflexly by dashing cold water over the face or chest, or by rubbing the face vigorously with a rough towel. The application of volatile substances, such as ammonia or smelling-salts, to the nose; the administration by the mouth of sal-volatile, whisky or brandy, and the intra-muscular injection of ether, are the most speedily efficacious remedies. In severe cases the application of hot cloths over the heart, or of

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